HIRAX 1500 IU – High-Purity Liquid Hyaluronidase for HA Filler Dissolution & Edema Management

HIRAX 1500 IU is a sterile liquid hyaluronidase injection containing 1,500 IU of hyaluronidase per 1 mL vial. Manufactured in South Korea, it is designed to increase tissue permeability, enhance dispersion of injected medications, promote reabsorption of excess fluids, and dissolve hyaluronic acid (HA) dermal fillers when correction or reversal is required.

Unlike many traditional hyaluronidase products supplied as lyophilized powder, HIRAX is provided as a ready-to-use liquid formulation, eliminating the need for reconstitution before administration.

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Key Benefits

• Dissolves hyaluronic acid fillers
• Corrects filler overcorrection and asymmetry
• Helps manage HA filler complications
• Promotes reabsorption of excess tissue fluids
• Supports treatment of swelling and bruising
• Enhances diffusion of injectable medications
• Ready-to-use liquid formulation
• High-purity hyaluronidase preparation
• No reconstitution required before use

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Product Specifications

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Mechanism of Action

Hyaluronic Acid Degradation

Hyaluronidase is an enzyme that hydrolyzes hyaluronic acid within connective tissues. This temporarily increases tissue permeability and facilitates absorption and diffusion within the treated area.

Filler Reversal

When injected into areas containing HA fillers, HIRAX breaks down the hyaluronic acid gel structure, allowing the body to gradually clear the degraded filler material. This makes it a standard reversal agent for unwanted HA filler results.

Fluid Reabsorption

HIRAX promotes reabsorption of excessive fluids and blood present within tissues, which is why hyaluronidase is also used in edema management and post-procedure swelling protocols.

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Common Aesthetic Uses

HIRAX 1500 IU is commonly used for:

• HA filler dissolution
• Correction of overfilled lips
• Tear trough filler correction
• Cheek filler adjustment
• Jawline filler correction
• Filler migration treatment
• Nodule management
• Vascular compromise protocols
• Management of excessive swelling after HA filler procedures

HIRAX only affects hyaluronic acid-based fillers and does not dissolve collagen stimulators such as PLLA, PDLLA, CaHA, PCL, or PMMA products.

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Available HIRAX Strengths

The HIRAX product line includes:

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Advantages of HIRAX 1500 IU

Compared with lower-strength formulations:

• Higher enzyme concentration per treatment session
• Suitable for larger treatment areas
• Often chosen for moderate-to-large filler corrections
• Reduced injection volume required to achieve a given IU dose
• Convenient liquid presentation with consistent concentration

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Storage

• Store according to manufacturer recommendations
• Protect from direct sunlight
• Maintain sterile conditions
• Use only within approved storage conditions specified by the manufacturer

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Safety Information

Possible treatment-related effects may include:

• Temporary redness
• Swelling
• Bruising
• Injection-site tenderness
• Allergic or hypersensitivity reactions

Because hyaluronidase can also break down naturally occurring hyaluronic acid in tissues, administration should only be performed by qualified healthcare professionals familiar with facial anatomy and complication management.

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Comparison: HIRAX 750 IU vs HIRAX 1500 IU

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Ideal Clinical Applications

HIRAX 1500 IU is often selected for:

• Moderate filler correction
• Multi-area HA filler dissolution
• Significant overcorrection cases
• Filler migration management
• Emergency filler complication protocols
• Swelling and edema reduction

The actual dose should always be determined by the treating practitioner according to the clinical situation.

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Important Notice

HIRAX 1500 IU is a professional-use medical product intended for administration by licensed healthcare professionals trained in aesthetic medicine, injectable treatments, and hyaluronidase protocols.