RADIESSE

RADIESSE – Calcium Hydroxylapatite (CaHA) Biostimulator for Facial Contouring & Collagen Stimulation

RADIESSE is a premium injectable calcium hydroxylapatite (CaHA) biostimulator and dermal filler developed to provide immediate volume restoration while simultaneously stimulating the body’s natural collagen production. Unlike traditional hyaluronic acid fillers, RADIESSE works through a dual-action mechanism that delivers instant correction and long-term skin rejuvenation.

Key Benefits

• Immediate volume restoration
• Long-term collagen stimulation
• Improves skin firmness and elasticity
• Enhances facial contours and definition
• Supports natural tissue regeneration
• Helps smooth moderate to severe wrinkles and folds
• Long-lasting aesthetic results
• Suitable for facial and hand rejuvenation

Common Applications

RADIESSE is commonly used for:

• Cheek augmentation
• Chin enhancement
• Jawline contouring
• Mid-face volume restoration
• Nasolabial folds
• Marionette lines
• Pre-jowl correction
• Hand rejuvenation
• Skin tightening protocols (hyperdiluted RADIESSE)

Product Specifications

• Product Name: RADIESSE®
• Type: Calcium Hydroxylapatite (CaHA) Dermal Filler & Biostimulator
• Active Ingredient:
  • 30% Calcium Hydroxylapatite Microspheres
  • 70% Aqueous Gel Carrier
• Concentration: 30% CaHA
• Syringe Size:
  • 1.5 ml syringe
  • 3.0 ml syringe (selected markets)
• Treatment Category:
  • Facial Contouring
  • Biostimulation
  • Volume Restoration
  • Hand Rejuvenation
• Manufacturer: Merz Aesthetics
• Origin: United States / Germany

Technology & Mechanism of Action

Immediate Volumization

The gel carrier provides an instant lifting and volumizing effect immediately after treatment, restoring lost facial volume and improving contour definition.

Collagen Biostimulation

The calcium hydroxylapatite microspheres act as a scaffold that stimulates fibroblast activity and encourages the production of new collagen over time.

Long-Term Tissue Remodeling

As the gel carrier gradually resorbs, newly formed collagen replaces the lost volume, contributing to improved skin quality, firmness, and structural support.

Key Ingredient

Calcium Hydroxylapatite (CaHA)

CaHA is a biocompatible mineral naturally found in human bones and teeth. In RADIESSE, smooth CaHA microspheres are suspended within a gel carrier and stimulate neocollagenesis following injection.

Benefits include:

• Enhanced structural support
• Increased collagen production
• Improved skin thickness
• Long-lasting volumization
• Natural-looking aesthetic outcomes

Treatment Areas & Injection Depth

Injection technique varies depending on treatment goals and practitioner preference.

Duration of Results

Results are often reported to last:

• Approximately 12–18 months in many facial applications
• Sometimes longer depending on treatment area, metabolism, injection technique, and individual response

Collagen stimulation may continue even after the initial gel carrier has been absorbed.

Hyperdiluted RADIESSE

RADIESSE can be diluted with saline and lidocaine to create a collagen-stimulating treatment often referred to as Hyperdiluted RADIESSE.

This technique is commonly used for:

• Neck rejuvenation
• Décolletage improvement
• Upper arms
• Abdomen
• Buttocks
• Thighs
• Skin laxity treatment

The primary goal is skin quality improvement rather than volume augmentation.

Administration

RADIESSE is intended for professional use and may be administered through:

• Needle injection
• Cannula techniques
• Facial contouring procedures
• Hand rejuvenation treatments
• Hyperdilution protocols

Only trained healthcare professionals should perform treatment.

Safety Information

Temporary treatment-related effects may include:

• Redness
• Swelling
• Bruising
• Tenderness
• Itching
• Firmness at injection sites

As with all injectable treatments, proper patient selection and injection technique are critical to minimizing complications.

Ideal Candidates

RADIESSE may be suitable for patients seeking:

• Facial contour enhancement
• Long-lasting volume restoration
• Collagen stimulation
• Improvement in skin firmness
• Non-surgical facial rejuvenation
• Hand rejuvenation

Treatment suitability should always be determined by a qualified medical professional.

Important Notice

RADIESSE® is intended strictly for use by licensed healthcare practitioners trained in aesthetic injectable procedures and facial anatomy.